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All
of the benefits of automated cell culture in a smaller
system ideal for the medium throughput cell culture
laboratory. |
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A new generation of
more compact robots has allowed TAP to downsize
the successful SelecT
system and enable the processing of T175 flasks
in a space only slightly larger than a standard
Class II safety cabinet. |
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CompacT
SelecT™ is the new automated cell culture
and assay- ready plating system designed to meet
the needs of medium throughput laboratories. It
has the capabilities of TAP’s established
SelecT cell culture system but with a lower capacity
and smaller footprint. Like SelecT, it improves
the reliability, accuracy and consistency of producing
cells. |
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The increasingly important
role in drug discovery of cell-based assays necessitates
a supply of cells of sufficient quality and quantity
not to become a limiting factor in downstream processes.
This requires the simultaneous maintenance and processing
of many different cell lines ideally 7 days a week
and at variable scales. CompacT
SelecT will automatically manage the whole
process from maintaining the cell lines to delivering
cells in plates on demand when required for assays. |
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CompacT
SelecT utilises the same automated protocols
as SelecT (culturing hundreds of thousands of flasks
without contamination) to grow and maintain cells
from multiple cell lines in T175 flasks in a controlled
environment (negative pressure laminar air flow)
eliminating all possibility for cross contamination.
It will count and check cell viability before dispensing
the cells into plates ready for cell-based screening
and assay development. |
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It
can hold up to 130 T 175 flasks in a temperature
and CO2 controlled incubator enabling
the simultaneous culture of multiple cell lines
limited only by the flask capacity and the number
of different media available from the 10 different
pumps. Virtually any attachment dependant cells
can be introduced onto the system without process
change and each flask can be processed with its
own unique parameters including timings, media and
volumes required by each cell type. |
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Output
from the system can be either as a harvested cell
suspension or in 96 or 384-well plates ready for
assay any day of the week. |
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CompacT
SelecT ensures a full
audit trail security via bar code tracking of flasks
and plates in the system. |
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- Expansion and maintenance of multiple cell
lines
- Sub culturing
- Expanding cell numbers through the seeding
of a number of flasks
- Transient transfection
- Harvesting and plating of cells for assays
and screening
- Harvesting of cells in flasks for off-line
processing
- Incubation of up to 130 T 175 flasks and
210 plates
- Cell counting and viability measurement
- Plating into 96 and 384-well plates
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- Total flexibility in batch size and numbers
of cell lines
- Full audit trail security via bar coded tracking
of flasks and plates
- Continuous unattended operation
- Small footprint 2.75m x 1.1m
- Integrated Multidrop™ cell dispenser
for 96 and 384-well plates
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CompacT
SelecT delivers dramatic
improvements in throughput, productivity and quality
for cell-based assays for drug discovery. |
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- Assay development
- Screening
- Lead optimisation
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What
are the differences in capacity of CompacT SelecT
compared to SelecT? |
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