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ambr
is a new system designed to mimic mammalian
cell culture in bioreactors at microscale
(10 – 15mL). It has been optimised
to reproduce suspension culture conditions
that exist within experimental 5 and 10
L bioreactors so that comparable results
can be obtained rapidly and at much lower
cost. 24 disposable micro bioreactors can
be controlled with an automated workstation
to allow many culture conditions and clones
to be screened in parallel. This enables
rapid, low cost optimisation of processes
to achieve productive suspension cell culture
systems for efficient reagent production. |
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For more information
visit: Cell
Culture Systems - ambr |
 |
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Cell-IQ
can be used for a wide range of imaging
applications in disease research as well
as for assay development. It is particularly
valuable where long term observations (days
or weeks) of live cells are needed and kinetic
data is important. |
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The system supports
cancer research
and can be used for cell migration studies,
cell tracking, vascularisation/angiogenesis,
cell death and dosing studies. In neurology
the system can be used to monitor neurite
production to study development and repair
of neural network. For compound
profiling and development, in vitro
toxicology models are becoming more widely
used and Cell-IQ is the ideal tool for developing
assays and kinetic studies using these new
tools. |
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For more information
visit: Cell
Culture Systems - Cell-IQ |
 |
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SelecT
has become the ‘gold standard’
for cell culture to provide cellular reagents
for cell-based screening. It has been installed
in over 40 laboratories including all the
major pharmaceutical research companies.
The system is used in a wide variety of
ways, both to provide cells for 1536 well
uHTS screening campaigns as well as maintaining
multiple cell lines (20+) in support of
therapeutic area research |
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HYPERflask and Triple flask
processing options can be added to increase
the incubation capacity and allow rapid
output of bulk cell suspensions. These can
be used directly in assay systems or for
freezing into cryovials as part of a frozen
cell screening strategy. |
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- ATCC
chose SelecT for their cell culture
production suite to manufacture stocks
of their most commonly requested cell
lines
- CAT chose
SelecT to produce large quantities of
cells daily for the screening of antibody
based drug candidates
- GSK chose
SelecT to provide consistent, high quality
cells for various receptor-based assays
|
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For more information
visit: Cell
Culture Systems - SelecT |
 |
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CompacT
SelecT has been widely implemented
to provide high quality cellular reagents
in assay-ready plates for high throughput
screening, lead optimisation and assay
development. From standard CHO stable
cell lines to embryonic stem cells, most
adherent mammalian cell lines can be easily
grown in the system, with minimal change
from the standard manual flask-based processing.
|
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HYPERflask and
Triple flask processing options can be added
to increase the incubation capacity and
allow rapid output of bulk cell suspensions.
These can be used directly in assay systems
or for freezing into cryovials as part of
a frozen cell screening strategy. |
| |
The new advanced
plating module (APM) provides greater
flexibility in plating output options including
media changes in standard plates as well
as maintenance of transport assay plates
such as Caco2. |
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CompacT
Cellbase is used for maintenance
and expansion of cells where output only
in flasks or harvested suspension is needed.
|
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- Solvay
(Laboratoires Fournier) chose
CompacT SelecT to increase the productivity
of their cell line maintenance and cell-based
screening activities
|
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For more information
visit: Cell
Culture Systems - CompacT SelecT and
CompacT
CellBase |
 |
| |
Cellmate
has been installed in over 80 sites around
the world for batch production of biologics
(protein therapeutics and vaccines), process
development and research. Cellmate is
used in research for producing large quantities
of cells for membrane assays. |
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Cellmate allows
flask-based (T flasks and roller bottles)
manual culture processes to be scaled up
from research to production without process
change for products that are difficult or
impractical to transition in to large scale
bioreactor production. |
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- Pfizer
chose Cellmate to prepare large,
uniform batches of many recombinant
cell lines to help increase the speed
and scale of their drug discovery efforts
|
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For more information
visit: Cell
Culture Systems - Cellmate |
|
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Cello
has been installed in a number of laboratories
to fully automate highly parallel automated
clone selection strategies. The creation
of stable cell lines with a range of growth
and expression characteristics optimised
to assay requirements require evaluation
of a large number of transfection events.
Cello manages the culturing and logistics
of working with 10,000’s of individual
clones to ensure that high quality candidates
are available for optimal assays. |
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For more information
visit Cell
Culture Systems - Cello |
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|
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Sonata,
has been optimised to grow suspension cultures
for production of reagents. The system automates
maintenance and expansion of mammalian and
insect cell lines. The system also automates
the production of protrin reagents in stable
and transfected cell lines, as well as baccolovirus
production and expression. |
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For more information
visit: Cell
Culture Systems - Sonata |
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For
more information on discovery and screening: |
| |
Get more
details on TAP's
Cell Culture Systems |
| |
Discuss
your requirements with Ian
Ransome, Sales Director |
| <<
Back to Key Applications in Cell Culture |
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